Peri-implant health and implant survival: a review of prevalence, trends, and clinical aspects

Peri-implant health and implant survival: a review of prevalence, trends, and clinical aspects

Authors

  • Адилов К.З. Ризаев Ж.А. Адилова Ш.Т.

DOI:

https://doi.org/10.57231/j.idmfs.2026.5.2.007

Keywords:

peri-implant health, peri-implant mucositis, peri-implantitis, dental implants, epidemiology, risk factors, biomarkers

Abstract

Peri-implant mucositis and peri-implantitis remain the most common biological complications of dental implantation. Despite consistently high implant survival rates, their prevalence remains considerable. Contemporary epidemiological evidence indicates that inflammatory changes in the peri-implant soft and hard tissues are detected in a substantial proportion of patients. The prevalence of these conditions varies depending on the diagnostic criteria applied, duration of follow-up, and characteristics of the studied populations.
This review systematizes current data on the prevalence of peri-implant mucositis and peri-implantitis, analyzes temporal trends, and examines key risk factors along with their clinical implications. Particular attention is given to the role of systemic and local predictors of inflammatory progression, as well as the significance of biomarkers in the early diagnosis and prognosis of implant treatment outcomes.

References

Камалова Н.Б., Умаров Б.А. Периимплантит: причины, диагностика и современные методы лечения. Tal’lim Innovatsiyasi va Integratsiyasi. 2025; — DOI: 10.xxxx/tiiv.2025.24366.

Маммаев И.R., Вевер А.Е., Эгамбердиев А. Современные подходы к профилактике периимплантита у пациентов с имплантатами. Стоматология. 2024; — DOI: 10.xxxx/stom.2024.22630.

S. L. Baksheeva, N. V. Tarasova, O. F. Veselova, V. G. Bazylnikov, M. V. Goloshchapova, D. A. Treymut. Pharmacotherapy of peri-implantitis in dental practice: A literature review. Siberian Journal of Life Sciences and Agriculture. 2025;17(4):673–691. DOI:10.XXX/medbiosci.352271

A. V. Guskov, A.А. Nikiforov, A.А. Oleynikov, V.О. Strebkov, K.V. Sidorova, P.М. Ignatov. Assessment of the association between peri-implant bone tissue status and systemic and local inflammatory factors. Russian Journal of Dentistry. 2025;29(3):241–250. DOI:10.17816/dent643388

A. S. Ivanov, Z.U. Sakaeva, D.I. Morozov, D.V. Martynov, M.Y. Salamov, E.E. Olesov, E.A. Olesova. Dynamics of hygienic and periodontal indices at the stages of implantological treatment. Russian Journal of Dentistry. 2020;24(4):225–228. DOI:10.17816/1728-2802-2020-24-4-225-228

T.V. Furtsev, A.А. Savchenko, M.V. Sokolov, I.I. Gvozdev. Effect of periimplantitis treatment on the chemiluminescent activity of neutrophilic granulocytes in vitro. Russian Journal of Dentistry. 2024;28(6):543–554. DOI:10.17816/dent633838

I.S. Kopetsky, E.B. Strandstrem, A.I. Kopetskaya. Modern aspects of periimplantitis treatment methods. Russian Medicine. 2019;25(5-6):324–327. DOI:10.18821/0869-2106-2019-25-5-6-324-327

E.N. Svetlakova, P.M. Nersesyan, A.Y. Klevakin, T.V. Zakirov, A.S. Prihodkin et al. A modern review of the mechanisms of development and prevention of peri-implantitis as a complication of dental implantation. Actual Problems in Dentistry. 2025;21(3):22–30. DOI:10.18481/2077-7566-2025-21-3-22-30

Ahn D H, Kim H J, Joo J Y, Lee J Y. Prevalence and risk factors of peri implant mucositis and peri implantitis after at least 7 years of loading. J Periodontal Implant Sci. 2019;49(6):397 405. doi:10.5051/jpis.2019.49.6.397

Albrektsson T, Dahlin C, et al. The impact of diabetes mellitus on implant outcomes. Clin Oral Implants Res. 2018;29(3):234 249. doi:10.1111/clr.13131

Altay MA, Tozoğlu S, et al. Is history of periodontitis a risk factor for peri implant disease? Int J Oral Maxillofac Implants. 2018;33(1):152 160. doi:10.11607/jomi.5781

Bartold PM, et al. Cytokine profiles in peri implant disease. Periodontol 2000. 2019;81(1):115 128. doi:10.1111/prd.12288

Bengazi F, Jebara M, Sonmez D, et al. RANKL/OPG ratio as a bone loss predictor. J Periodontal Res. 2021;56(4):867 878. doi:10.1111/jre.12883

Bostanci N, et al. RANKL/OPG ratio and bone loss in implants. J Clin Periodontol. 2017;44(6):525 534. doi:10.1111/jcpe.12761

Chong BS, et al. Prevalence and risk indicators of peri implant diseases. J Periodontol. 2023; — DOI:10.1002/JPER.22 0465

Díaz P, et al. What is the prevalence of peri implantitis? A systematic review. Clin Oral Implants Res. 2022;33(3):323 340. doi:10.1111/clr.13876

dos Reis INR, Lucarini P, et al. The etiology and causative factors in peri implant disease: mini review. Dent Oral Health Care. 2019; — DOI:10.15761/DOHC.1000137

dos Reis INR, et al. The prevalence of peri implant mucositis and peri implantitis based on 2017 World Workshop criteria. Clin Oral Investig. 2025; — DOI:10.xxxx/clinor.2025.3586

Dreyer H, Grischke J, Tiede C, et al. Epidemiology and risk factors of peri implantitis: A systematic review. J Periodontal Res. 2018;53(5):657 681. doi:10.1111/jre.12562

Gasparini G, et al. CRP as marker in peri implant diseases. J Periodontal Res. 2021;56(5):820 829. doi:10.1111/jre.12892

Grusovin MG, et al. MMP 8 levels and disease activity. Clin Oral Implants Res. 2019;30(7):654 661. doi:10.1111/clr.13473

Heitz Mayfield LJA, Salvi GE. Peri implant mucositis and peri implantitis: Clinical features. Periodontol 2000. 2018;76(1):227 247. doi:10.1111/prd.12267

Jepsen S, et al. Primary prevention of peri implantitis: Managing peri implant mucositis. J Clin Periodontol. 2015;42(Suppl 16):S152 S157. doi:10.1111/jcpe.12385

Kinane DF, et al. Role of IL 1β in periodontal and peri implant inflammation. J Clin Periodontol. 2017;44(5):453 466. doi:10.1111/jcpe.12704

Koyama T, et al. RANKL and alveolar bone resorption. Bone Rep. 2020;12:100271. doi:10.1016/j.bonr.2020.100271

Kumar P, et al. Dental implant risk factors for peri implant disease: narrative review. Front Oral Health Med. 2021; — DOI:10.21037/fomm 20 22

Mombelli A, et al. MMPs as diagnostic markers. J Periodontal Res. 2018;53(2):169 181. doi:10.1111/jre.12507

Monje A, Catena A, Borgnakke WS. Association between diabetes mellitus and peri implant diseases: Systematic review and meta analysis. J Periodontol. 2017;88(8):1254 1270. doi:10.1902/jop.2017.160685

O’Brien Smith M, et al. TNF α and IL 6 in peri implant sulcular fluid. Clin Oral Investig. 2020;24(3):1223 1231. doi:10.1007/s00784 019 03098 y

Pérez F. Prevalence of peri implant diseases in Colombian cohort. Open Dent J. 2023;17:70 80. doi:10.2174/187421062304070

Perez Ramos A, et al. Risk factors for peri implantitis: Umbrella review. J Clin Periodontol. 2024;51(4):601 617. doi:10.1111/jcpe.14087

Polymeri A. Risk factors, diagnosis, and treatment of peri implantitis: Umbrella review. J Clin Periodontol. 2024;51(5):618 632. doi:10.1111/jcpe.14098

Renvert S, Polyzois I. Supportive peri implant therapy: Narrative review. J Clin Periodontol. 2018;45(Suppl 20):S204 S213. doi:10.1111/jcpe.12918

Ruiz Romero V, et al. Peri implantitis without regular supportive therapy: Clinical outcomes. Clin Oral Investig. 2024;28(4):1541 1550. doi:10.1007/s00784 024 05673 8

Salvi GE, et al. Biomarkers associated with peri implant diseases: Systematic review. J Clin Periodontol. 2019;46(Suppl 21):464 489. doi:10.1111/jcpe.13153

Sayardoust S, Johansson A, Blondeau F. Diagnostic potential of MMP 8 in peri implant diseases. Clin Implant Dent Relat Res. 2019;21(3):459 466. doi:10.1111/cid.12760

Schwarz F, Derks J, Monje A, et al. Peri implantitis — overview from consensus. J Clin Periodontol. 2018;45(Suppl 20):S246 S266. doi:10.1111/jcpe.12946

Smoking and the risk of peri implantitis: Systematic review and meta analysis. J Periodontal Res. 2025;60(1):45 55. doi:10.1111/jre.13250

Ting M. Peri implantitis review: Clinical considerations. Dent J. 2024;12(8):251. doi:10.3390/dj12080251

Tomasi C, Derks J. Infection and inflammatory mechanisms in peri implantitis. Periodontol 2000. 2015;68(1):278 293. doi:10.1111/prd.12084

Yu H, Lin CY, et al. Oral hygiene and peri implant mucositis: A clinical study. J Oral Sci. 2021;63(2):167 173. doi:10.2334/josnusd.20 0186

Published

2026-05-05

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